Review of Ativisha (Aconitum Heterophyllum) – And Its Therapeutic Potential

Abstract

India's medical history dates back thousands of years, with the Rigveda being the oldest recorded reference of medicinal usage. Ayurveda, an Upveda, includes about 6000 species of medicinal plants. Ativisha, a tall herb made from dried, tuberous roots of the perennial herb Aconitum heterophyllum Wall. Ex. Royle is highly recommended for preventing debility following a fever and has various pharmacological characteristics and therapeutic indications. Ativisha is mentioned in every ancient compendium, including the Vedas and the Ayurvedic Chikitsa Grantha. Phytochemistry of Aconitum heterophyllum includes a diverse array of bioactive chemicals, especially alkaloids, contributing to its traditional uses and medicinal qualities. The plant has a long history of traditional applications in medical systems, including Ayurveda and Traditional Chinese Medicine (TCM). It has been used to treat digestive disorders, respiratory disorders; anti-inflammatory and analgesic properties, diarrhea and dysentery, gastrointestinal disorders, antispasmodic agents, malaria, and febrile diseases. Pharmacological effects of Aconitum heterophyllum include strong anti-inflammatory and analgesic effects, as well as antipyretic properties. Its extracts and alkaloids have shown inhibitory actions against specific disease-causing microbes, making it a potential candidate for the development of antimicrobial drugs.