Impact of Nutritional Interventions on Tissue Repair and Wound Healing: A Comprehensive Review.

Abstract

Wound healing is a dynamic and multifactorial process requiring a complex interaction between cellular and molecular mechanisms. Nutrition plays a critical role in optimizing these processes, supporting tissue repair, immune function, and reducing recovery time. This review explores the impact of various nutritional interventions on wound healing, with a focus on macronutrients, micronutrients, amino acids, and specialized supplements. We discuss their specific roles in the hemostasis, inflammation, proliferation, and remodeling phases of healing. Additionally, we highlight emerging nutritional therapies and their clinical relevance, underscoring the importance of personalized nutrition for enhancing healing outcomes. The clinical implications of nutritional strategies, particularly in surgical and chronic wound care, are also explored.