Comparative Efficacy of Micro-Invasive Resin Infiltration Techniques on Acid Resistance and Enamel Microhardness in Orthodontic-Induced White Spot Lesions: An In Vitro Study.

Authors

  • Ahmed Akram El-Awady, Eslam Hassan Gabr, Mohamed Mohamed Ali, Khaled Mohammad Taha, Abdallah Mohammed Bahaa El-Din , Ahmed Talaat Hussein , Mahmoud M. Fathy Aboelmahasen, Ahmed Mohamed Naguib, Alaa Mohammed El Hendawey, Khaled Samy ELHabbak Author

DOI:

https://doi.org/10.64149/J.Carcinog.24.2s.1330-1341

Keywords:

Orthodontic white spot lesions, Icon resin infiltration, composite sealant, acid resistance, microhardness

Abstract

Background: White spot lesions (WSLs) affect 38–96% of orthodontic patients. They form around brackets within 4 weeks due to plaque accumulation in difficult to clean areas, leading to aesthetic issues and compromised treatment outcomes.

Objectives: This research was conducted to compare the effect of Icon versus composite resin sealant as resin infiltration

 

systems on the ability to protect orthodontic induced WSLs against acid attacks.

Materials and methods: The study involved 120 premolars and 40 premolars from them were divided into 2 control groups (n=20): Group (1) un-demineralized enamel (positive control), Group (2) untreated WSLs (negative control). The remaining 80 premolars were divided into two treatment groups according to the material used in WSLs treatment (n=40); Group (3) Icon, and Group (4) Permaseal composite resin sealant. Groups (3 and 4) were further subdivided into two subgroups (n=20): tested before and after the acid exposure (Coca-Cola). Vickers microhardness evaluation was performed before demineralization, after demineralization, after Icon and Permaseal treatment, and after acidic exposure.

Results: The Icon and Permaseal groups exhibited significantly higher microhardness values than the negative control group but significantly lower than the positive control group. Nevertheless, a non-significant difference was found between them. However, the acidic exposure significantly decreased the microhardness values in the Icon and Permaseal subgroups, while the Permaseal subgroup showed the significantly lowest values. The Icon subgroup showed higher microhardness values compared to the negative control group, while the Permaseal subgroup showed non-significant higher difference.

Conclusions: Both Icon resin infiltration and Permaseal composite sealant effectively improved the microhardness of artificially induced orthodontic WSLs compared to untreated lesions. However, Icon resin infiltration exhibited superior resistance to acidic exposure, maintaining significantly higher microhardness post-acidic challenge than Permaseal.

Downloads

Published

2025-08-28

How to Cite

Comparative Efficacy of Micro-Invasive Resin Infiltration Techniques on Acid Resistance and Enamel Microhardness in Orthodontic-Induced White Spot Lesions: An In Vitro Study. (2025). Journal of Carcinogenesis, 24(2s), 1330-1341. https://doi.org/10.64149/J.Carcinog.24.2s.1330-1341

Similar Articles

1-10 of 243

You may also start an advanced similarity search for this article.