Effects of experimental gastric acid pH on fixed indirect restorative materials made using CAD/CAM: Systematic review

Authors

  • Martha Alejandra Cornejo Córdova* Author
  • Katherine Andrea Romero Espinoza Author
  • Wilson Rolando Naranjo Andrade Author
  • Paula Geovanna Zabala Yánez Author

DOI:

https://doi.org/10.64149/J.Carcinog.24.3s.79-102

Keywords:

Acid degradation, Aesthetic properties, Bulimia, CAD/CAM, Gastroesophageal Reflux, GERD, Mechanical properties, Physical properties.

Abstract

Objective: To analyze how acidic pH affects the stability and properties of CAD/CAM restorative materials. Methods: This review followed PRISMA 2020. Searches were run in MEDLINE (via PubMed), ScienceDirect, and Web of Science using MeSH and free-text terms. In addition, the JBI critical appraisal checklist was used for quality assessment, based on the types of items analyzed. Results: After applying the inclusion and exclusion criteria, the review focused on 15 articles, including randomized clinical trials, quasi-experimental studies, and a narrative review of the literature, primarily high-level studies. Conclusion:. Zirconia and lithium disilicate showed superior aesthetic stability, flexural strength, and surface integrity under acidic conditions, while feldspathic and resin-matrix materials were more susceptible to degradation. Glazing helped reduce surface deterioration. The lack of standardized methodologies limits comparability, highlighting the need for future research to guide clinical recommendations.

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Published

2025-09-09

How to Cite

Effects of experimental gastric acid pH on fixed indirect restorative materials made using CAD/CAM: Systematic review. (2025). Journal of Carcinogenesis, 24(3), 79-102. https://doi.org/10.64149/J.Carcinog.24.3s.79-102

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