Exploring High-Efficiency Organic LEDs for Cancer Biomarker Detection: A Comparative and Functional Analysis

Abstract

This study presents a performance analysis and comparative evaluation of third-generation thermally activated delayed fluorescence (TADF) organic light-emitting diodes (LEDs) against previous generations of organic-LED technologies. The evolution of organic-LEDs has significantly transformed display, lighting, and biomedical applications, with TADF materials, particularly carbazole derivatives, emerging as promising candidates for achieving high efficiency through the utilization of both singlet and triplet excitons. The research highlights the potential of TADF organic-LEDs in enhancing cancer detection and treatment via photodynamic therapy, showcasing their unique optical properties that improve sensitivity in identifying cancer biomarkers. Despite advancements, challenges such as efficiency roll-off at elevated drive currents persist, necessitating ongoing investigations into material stability, triplet population management, and device architecture optimization. The findings underscore the importance of interdisciplinary collaboration in advancing TADF organic-LED technology, paving the way for innovative applications in personalized medicine and improved therapeutic outcomes. Overall, this study contributes to the foundational understanding required for the continued development and commercialization of TADF organic-LEDs in high-performance applications.