Association Between Abo Blood Group And The Risk Of Colo Rectal Cancer – An Institutional Study

Abstract

Introduction - Colorectal cancer is the second most frequent cancer in women and the third most common cancer in males. The incidence of colorectal cancer is rapidly rising in developing countries like India. The blood group system serves as a distinguishing marker of identification, providing an essential component of an individual's personality and distinctiveness. the aim of the present study is to assess the the distribution of the ABO blood group system (A, B, O or AB) and Rhesus type (Rh-positive or Rh-negative Rh+ or Rh-) in subjects with colorectal cancer.

Methodology - The present study is a retrospective record based study on subjects with colorectal carcinoma at Sri Devaraj URS Academy of Higher Education & Research, Kolar in Karnataka which was conducted over a period of 5 years study (2017 – 2022). The clinical data were obtained from subject’s files who met the above mentioned inclusion criteria and also subjects who agreed to participate in the study, using the pre-structured questionnaire to minimize data errors.

Results - Out of 67 subjects, 34.3% belongs to A group, whereas 7.5% belongs to AB group, 17.9% belongs to B group and 40.3% belongs to O group.80.6% of the study subjects were found to be RH positive whereas 19.4% of the study subjects were RH negative.

Conclusion - Our study found no link between ABO and Rh blood groups and colorectal cancer. While our findings contradict those populations that show a positive association, it is crucial to recognise that different factors can influence different elements of colorectal cancer.