Where did the super-small sized large bowel advanced cancer come from?

Abstract

Although most of the large bowel advanced cancers (the carcinoma invaded into the muscularis propria or deeper zone by Japanese criteria [1]), or T2 and T3 by UICC classification [2]) are 3 – 6 cm in maximum (max.) diameter, those less than 2 cm in max. diameter were sometimes found, today. However, nobody knows what is the pre-lesion of these small sized large bowel advanced cancer.

In the current study, using the characteristics of the histological features of the large bowel cancers with invasion to the submucosal layer (SM-C), the histogenesis of the super-small sized large bowel advanced cancers less than 15 mm in max. diameter (SS-AC) were analyzed pathologically, and some findings were revealed for clearing the question described above.