Effectiveness of Bioactive Glass Based Dentifrice With and Without Chitosan Nanoparticles in Restoring Enamel Microhardness Post Bleaching: An In Vitro Study

Abstract

Aim: To evaluate the effectiveness of a bioactive glass-based dentifrice, with and without the addition of chitosan nanoparticles, in restoring enamel hardness after bleaching with 37.5% hydrogen peroxide.

Material And Methods: Fifteen extracted human maxillary central incisors were divided into three groups: control (no treatment), treatment with bioactive glass-based dentifrice and treatment with bioactive glass-based dentifrice infused with 0.2% chitosan nanoparticles. Enamel microhardness was measured at baseline, post-bleaching, and post-remineralization using a Vickers microhardness tester.

Results:  All study groups showed significant enamel demineralization post-bleaching. Remineralization using both formulations improved enamel hardness, with chitosan-infused dentifrice showing slightly superior recovery.

Conclusion: These findings suggest that bioactive glass-based dentifrices, particularly when combined with chitosan nanoparticles, offer a viable strategy for mitigating the deleterious effects of dental bleaching.