Entropy Analysis of MHD Flow of Hybrid Nanofluid on a Stretching Cylinder with Slip Effects

Abstract

The properties of entropy generation within the magnetohydrodynamic (MHD) motion of a hybrid nanofluid across a porous stretched cylinder are examined in this work, with a special emphasis on biomedical applications such as cancer treatment. The model incorporates slip boundary conditions, chemical reaction effects, and viscous dissipation. The hybrid nanofluid comprises two nanoparticles copper and aluminium oxide, dispersed in a base fluid. This composition enhances thermal conductivity as well as mass transport, rendering it ideal for biomedical hyperthermia, which utilises localised heating to eliminate cancerous cells.  This study analyses the effect of magnetic field magnitude, porosity, slip parameters, chemical reactions rate, along with viscous dissipation on the entropy produced, heat transfer, as well as concentration distribution through similarity transformations along with numerical techniques. The interplay between magnetic field forces and nanoparticle concentration is evaluated to highlight their combined effect on controlling heat generation and reducing irreversibilities within the system. The results demonstrate that tuning the magnetic and thermophysical parameters can regulate the velocity, temperature, and concentration fields, thereby enabling controlled thermal therapy. Sensitivity analysis identifies the dominant factors influencing entropy generation and boundary layer thickness. The findings not only validate the accuracy of the present model against previous literature but also provide novel insights into the use of MHD hybrid nanofluid flows in biomedical systems, particularly in optimizing thermal efficiency and precision during cancer hyperthermia treatments.