Association between MRI intensity change in the spinal cord on T1 and T2 images and myelopathic severity in patients with cervical spondylotic diseases

Authors

  • Mohammad Abu Taher Miah*, Abu Saleh Mohammad Abu Obaiaida, Md. Ruhul Kuddus, Md. Rezaul Amin, Kh. Olinur Razib, Md. Mahbub Hasan, Rubaiyat-E-Mortaz Author

DOI:

https://doi.org/10.64149/J.Carcinog.24.5s.553.562

Keywords:

CSD, Nurick Grades, Myelopathy, MRI.

Abstract

Background: Cervical Spondylotic Myelopathy (CSM) is a prevalent degenerative spinal condition characterized by spinal cord compression. The accurate diagnosis and timely treatment of CSM are challenging due to its gradual progression. The aim of this study is to identify the association between signal intensity changes in the spinal cord on T1- and T2-weighted MRI images and motor myelopathic severity in patients with cervical spondylotic disease (CSD).

Methods: This study was a cross-sectional descriptive type of study. It included 30 patients. The study was carried out in the Department of Neurosurgery, Bangabandhu Sheikh Mujib Medical University, Dhaka.

Results: The mean±SD age of the patients was 44.83±11.87 years, Out, 13 (43.33%) were aged 40 years or younger, while 17 (56.67%) were older than 40 years. The data showed that no patients were classified as Nurick grade 0 or 1. Five patients (16.67%) were graded as 2, while the majority of patients, sixteen patients were (53.33%) into grade 3, the majority of patients in this study. Eight patients (26.67%) were classified as grade 4, and one patient (3.33%) had the most severe grade of 5. Notably, hyper-intense T2 signal changes were observed in 21 patients, predominantly in those with Nurick grades 3 and 4. No patients showed only T1 signal changes. The p-value of 0.2 indicates insignificant association between MRI signal changes and Nurick grading severity.

Conclusion: In conclusion, this study reveals that there was no significant association between T2 signal intensity changes on spinal cord MRI and motor myelopathy severity in cervical spondylotic disease patients.

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Published

2025-07-15

How to Cite

Association between MRI intensity change in the spinal cord on T1 and T2 images and myelopathic severity in patients with cervical spondylotic diseases. (2025). Journal of Carcinogenesis, 24(5s), 1165-1170. https://doi.org/10.64149/J.Carcinog.24.5s.553.562

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