Orbital Exenteration for Massive, Recurrent Basal Cell Carcinoma with Perineural Invasion: A Case Report

Abstract

Basal cell carcinoma (BCC) of the periocular region, though typically indolent, may behave aggressively in recurrent or large tumors. We present a case of massive, recurrent periocular BCC with perineural invasion necessitating orbital exenteration. Histopathological examination revealed infiltrative basaloid cell nests with perineural invasion, despite negative surgical margins. This report highlights the importance of recognizing high-risk pathological features in guiding radical surgical intervention.