Medicinal plant in cancer pharmaceutical industry in Indonesia: a systematic review on applications and future perspectives

Jamilah Nasution1, Eva Sartika Dasopang2, Anita Restu Puji Raharjeng3, Kasta Gurning4, Gabena Indrayani Dalimunthe5, Ikbar Pratama6
1Fakultas Sains dan Teknologi, Universitas Medan Area, Medan,Sumatera Utara, Indonesia
2Fakultas Farmasi, Universitas Tjut Nyak Dhien, Indonesia
3Fakultas Saintek, UIN Raden Fatah Palembang, Indonesia
4Departemen Farmasi, Sekolah Tinggi Ilmu Kesehatan Senior Medan, Indonesia

5Faculty of Pharmacy, Universitas Muslim Nusantara AL Washliyah, Indonesia
6Fakultas Ekonomi dan Bisnis, Universitas Medan Area, Medan, Sumatera Utara, Indonesia
DOI: 10.4103/jcar.jcar_8_21

ABSTRACT

PURPOSE: This paper aims to write a systematic review paper on the uses, sources, and importance of Medicinal Plants in Cancer Treatments and their role in the Indonesian Pharmaceutical Industry.
METHODOLOGY: This paper is based on Qualitative Research Analysis. Furthermore, it reviews 70 papers based on the conceptual background of Medicinal Plants.
FINDINGS: Medicinal plants have long been used to treat a range of maladies, and they are one of the most important sources of novel pharmacologically active chemicals identified and exploited in the development of new pharmaceuticals by the pharmaceutical industry. Compounds isolated from the Medicinal Plant have been proven to have anti-cancer properties, such as inhibiting cancer cell proliferation and triggering apoptotic cell death.
ORIGINALITY/VALUE: This paper provides knowledge about Medicinal Plants and allows the pharmaceutical industry to practically use the Medicinal Plants to extract the drugs used to cure cancer.

Keywords:Medicinal Plant, Cancer, Indonesia, Pharmaceutical Industries, Invasion Characteristics, Medical Services.