Abstracts – Invited Speakers
ABSTRACT Department of Biochemistry, Indian Institute of Science, Bangalore, India Immunotherapy is fast emerging as one of the leading modes ...
p53 and regulation of tumor metabolism
Peng Jiang, Wenjing Du, Xiaolu YangDepartment of Cancer Biology, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of ...
Role of chemokine receptor CXCR2 expression in mammary tumor growth, angiogenesis and metastasis
Kalyan C Nannuru, Bhawna Sharma, Michelle L Varney, Rakesh K SinghDepartment of Pathology and Microbiology, The University of Nebraska Medical ...
A block in lineage differentiation of immortal human mammary stem / progenitor cells by ectopically-expressed oncogenes
Xiangshan Zhao1, Gautam K Malhotra1, Hamid Band2, Vimla Band31Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, ...
Shared signaling pathways in normal and breast cancer stem cells
Gautam K Malhotra1, Xiangshan Zhao1, Hamid Band2, Vimla Band31Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, ...
Oncogenic activation of ERG: A predominant mechanism in prostate cancer
Taduru L Sreenath, Albert Dobi, Gyorgy Petrovics, Shiv SrivastavaCenter for Prostate Disease Research, Department of Surgery, Uniformed Services University of ...
Emerging candidates in breast cancer stem cell maintenance, therapy resistance and relapse
Bhawna Sharma, Rakesh K SinghDepartment of Pathology and Microbiology, The University of Nebraska Medical Center, 985900 Nebraska Medical Center, Omaha, ...
Mouse models of estrogen receptor-positive breast cancer
Shakur Mohibi1, Sameer Mirza1, Hamid Band2, Vimla Band31Department of Genetics, Cell Biology, and Anatomy, College of Medicine, University of Nebraska ...
MicroRNA alterations in Barrett’s esophagus, esophageal adenocarcinoma, and esophageal adenocarcinoma cell lines following cranberry extract treatment: Insights for chemoprevention
Laura A Kresty1, Jennifer Clarke1, Kristin Ezell1, Amy Exum1, Amy B Howell2, Toumy Guettouche31Department of Epidemiology and Public Health, University ...
Hormones and prostate carcinogenesis: Androgens and estrogens
Maarten C Bosland, Abeer M MahmoudDepartment of Pathology, University of Illinois at Chicago 840 South Wood Street Room 130 CSN, ...
The two faces of Janus kinases and their respective STATs in mammary gland development and cancer
Kay-Uwe Wagner, Jeffrey W SchmidtEppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 985950 Nebraska ...
Paget’s disease of the breast
Cansu KarakasDepartment of Experimental Radiation Oncology at University of Texas MD Anderson Cancer Center, Houston, TX, USA.DOI: 10.4103/1477-3163.90676 ABSTRACT Paget's ...
Diabetes mellitus and gastric carcinoma: Is there an association?
Sathiya P Marimuthu1, Paari Vijayaragavan2, Kirsten B Moysich3, Vijayvel Jayaprakash41Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, ...
Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer
Cesar F Ortega-Cava1, Srikumar M Raja2, Zenab Laiq1, Tameka A Bailey1, Haitao Luan3, Bhopal Mohapatra4, Stetson H Williams1, Aaron C ...
Mechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance
Tameka A Bailey1, Haitao Luan2, Robert J Clubb1, Mayumi Naramura3, Vimla Band3, Srikumar M Raja4, Hamid Band51Eppley Institute for Research ...
Chemoprevention of prostate cancer: Natural compounds, antiandrogens, and antioxidants – In vivo evidence
Nur Özten-Kandas, Maarten C BoslandDepartment of Pathology, University of Illinois at Chicago, Chicago, IL, USA.DOI: 10.4103/1477-3163.90438 ABSTRACT Prostate cancer is ...
Exploration of structural stability in deleterious nsSNPs of the XPA gene: A molecular dynamics approach
N NagaSundaram1, C George Priya Doss21School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India2Center for Nanobiotechnology, Medical Biotechnology ...
Breaking the cycle: An insight into the role of ERα in eukaryotic cell cycles
Sonia Javan Moghadam, Amanda M Hanks, Khandan KeyomarsiDepartment of Experimental Radiation Oncology at University of Texas MD Anderson Cancer Center, ...
Cyclin D1 inhibits whereas c-Myc enhances the cytotoxicity of cisplatin in mouse pancreatic cancer cells via regulation of several members of the NF-κB and Bcl-2 families
Ayman El-Kady1, Yuan Sun2, Ying-xia Li3, D Joshua Liao21Department of the University of Minnesota, Hormel Institute, Austin, MN 55912, USA; ...
Optimizing therapeutic efficacy of chemopreventive agents: A critical review of delivery strategies in oral cancer chemoprevention clinical trials
Andrew S Holpuch1, Kashappa-Goud H Desai2, Steven P Schwendeman2, Susan R Mallery31Division of Oral Maxillofacial Surgery, Pathology and Anesthesiology, College ...
Toward the identification of communities with increased tobacco-associated cancer burden: Application of spatial modeling techniques
Noella A Dietz1, Recinda Sherman2, Jill MacKinnon2, Lora Fleming3, Kristopher L Arheart1, Brad Wohler2, David J Lee11Department of Epidemiology and ...
The manner in which calories are restricted impacts mammary tumor cancer prevention
Margot P Cleary, Michael E GrossmannUniversity of Minnesota Hormel Institute, 801 16th Ave. NE Austin, MN 55912-3679, USA.DOI: 10.4103/1477-3163.85181 ABSTRACT ...
Androgen receptor signaling in prostate cancer development and progression
Peter E Lonergan, Donald J TindallDepartment of Urology, Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.DOI: 10.4103/1477-3163.83937 ABSTRACT The ...
Development of angle-resolved low coherence interferometry for clinical detection of dysplasia
Yizheng Zhu, Neil G Terry, Adam WaxDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.DOI: 10.4103/1477-3163.83935 ABSTRACT This review covers ...
Cell phones are as carcinogenic as coffee
Gopala KovvaliDepartment of Genetics, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854-8082; Carcinogenesis Foundation, 614 Overdell Drive, Sugar Land, TX, ...
Metformin as an energy restriction mimetic agent for breast cancer prevention
Zongjian Zhu1, Weiqin Jiang1, Matthew D Thompson2, John N McGinley1, Henry J Thompson11Cancer Prevention Laboratory, Colorado State University, Fort Collins, ...
Abstracts – Poster Presentations
ABSTRACT Oral submucous fibrosis is a chronic, progressive, scarring disease that affects people of South-East Asia predominantly. It is a ...
Elevated levels of urinary 8-hydroxy-2′-deoxyguanosine and 8-isoprostane in esophageal squamous cell carcinoma
Mohammad-Hassan Khadem-Ansari1, Zahra Shahsavari1, Yousef Rasmi1, Rahim Mahmoodlo21Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.2Department ...
Therapeutic prevention of colorectal carcinogenesis
Frank L MeyskensDepartment of Medicine, Biological Chemistry, and Public Health, Chao Family Comprehensive Cancer Center, University of California, Irvine - ...
Statistical methods for assays with limits of detection: Serum bile acid as a differentiator between patients with normal colons, adenomas, and colorectal cancer
Bonnie LaFleur1, Wooin Lee2, Dean Billhiemer3, Craig Lockhart4, Junmei Liu5, Nipun Merchant61Department of Epidemiology and Biostatistics, BIO5, University of Arizona, ...
Perspective: Chemoprevention of colorectal neoplasia: Translating scientific promise into clinical practice
Peter Lance, Patricia A ThompsonArizona Cancer Center, University of Arizona, Tucson, AZ, USA.DOI: 10.4103/1477-3163.79674 ABSTRACT With more than 145,000 new ...
Defining the role of polyamines in colon carcinogenesis using mouse models
Natalia A Ignatenko1, Eugene W Gerner1, David G Besselsen21Department of Cell Biology and Anatomy, Arizona Cancer Center, 1515 N. Campbell ...
The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies
Mariangela De Robertis1, Emanuela Massi1, Maria Luana Poeta2, Simone Carotti3, Sergio Morini3, Loredana Cecchetelli4, Emanuela Signori5, Vito Michele Fazio61Laboratory of ...
Clinical trials update: Tertiary prevention of colorectal cancer
Jason A ZellDepartment of Medicine and Epidemiology, School of Medicine, Chao Family Comprehensive Cancer Center, University of California, Irvine, CA ...
Systematic enrichment analysis of gene expression profiling studies identifies consensus pathways implicated in colorectal cancer development
Jesús Lascorz1, Kari Hemminki2, Asta Försti21Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany2Division of Molecular Genetic ...
Risk of second primary colorectal cancer among colorectal cancer cases: A population-based analysis
Kavitha P Raj1, Thomas H Taylor2, Charlie Wray3, Michael J Stamos4, Jason A Zell51Chao Family Comprehensive Cancer Center, Division of ...
Wnt signaling and colon carcinogenesis: Beyond APC
Rani Najdi1, Randall F Holcombe2, Marian L Waterman11Department of Microbiology and Molecular Genetics, University of California, Irvine, USA.2Tisch Cancer Institute, ...
Role of protein kinase C β and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism
Sivakumar Loganathan1, Rajani Kanteti1, Shahid S Siddiqui2, Essam El-Hashani1, Maria Tretiakova3, Hari Vigneswaran1, Gustavo Cervantes1, Viswanathan Natarajan2, Aliya N Husain3, ...
Circulating fibroblast growth factor-23 is associated with increased risk for metachronous colorectal adenoma
Elizabeth Jacobs, Maria Elena Martinez, Julie Buckmeier, Peter Lance, Melissa May, Peter JurutkaEpidemiology and Biostatistics, Mel and Enid Zuckerman College ...
Zoledronic acid directly suppresses cell proliferation and induces apoptosis in highly tumorigenic prostate and breast cancers
Hussain Almubarak1, Antonia Jones1, Risa Chaisuparat2, Ming Zhang1, Timothy F Meiller1, Mark A Scheper11University of Maryland and the Marlene and ...
Inhibitory effects of Indigofera aspalathoides on 20-methylcholanthrene-induced chemical carcinogenesis in rats
S Selva Kumar1, CM Karrunakaran1, M. R. K. Rao1, MP Balasubramanian21Department of Industrial Biotechnology, Bharath University, Chennai 600 073, India2Department ...