Systematic Review of Cognitive and Sensory Approaches in Alzheimer's Therapy

Abstract

Purpose: This systematic review examines the effectiveness of cognitive and sensory therapeutic interventions in managing Alzheimer's disease progression and improving quality of life for patients. The study aimed to synthesize current evidence on non-pharmacological approaches that engage cognitive functions and sensory modalities in Alzheimer's care.

Methods: A comprehensive literature search was conducted across PubMed, PsycINFO, and Cochrane databases from 2019-2024. Studies examining cognitive stimulation therapy, sensory interventions, and multimodal approaches in Alzheimer's patients were included. Quality assessment was performed using the Cochrane Risk of Bias tool.

Results: Fifteen studies met inclusion criteria, encompassing 2,847 participants across various stages of Alzheimer's disease. Cognitive stimulation therapy showed significant improvements in MMSE scores (mean difference 2.3 points, p<0.05). Sensory interventions, particularly music therapy and aromatherapy, demonstrated effectiveness in reducing behavioral symptoms and improving mood. Multimodal approaches combining cognitive and sensory elements yielded the most promising outcomes.

Conclusions: Cognitive and sensory approaches represent valuable non-pharmacological interventions for Alzheimer's therapy. While individual interventions show moderate benefits, integrated multimodal approaches demonstrate superior outcomes in cognitive function, behavioral management, and quality of life measures