Anaam Mahdi Dawood 1, Mohammed Abdul razzaq Assi 2
1Department of Anesthesia Techniques, College of Health and Medical Techniques/ Kufa, Al_Furat Al_Awsat Technical University, 31003 Al-Kufa, Iraq
2Department of Medical Laboratory Techniques, College of Health and Medical Techniques/ Kufa, Al_Furat Al_Awsat Technical University, 31003 Al-Kufa, Iraq
ABSTRACT
Background: Among women, infertility rises by 0.370%, while among men; it rises by 0.291% per year. Idiopathic variables, such as smoking, drinking, using drugs, being overweight, experiencing stress at work or at home, becoming older, and consuming certain foods, are certain of the reasons of men fertility SPTΡRX3, a unique member of the thioredoxin family, specifically found in the testis and male germ line, accumulates in the external area of malfunctioning sperm cells. Subjects and Method: Two groups, totaling 80 participants, participated in this study. The first group is the patient group, which consists of 40 infertile individuals and 40 healthy control males. A specialist fertilization doctor determined the infertility of the men by samples collection at fertilization Center at Al-Sader Medical City in Al-Najaf city. Results: Infertile men had considerably higher levels of TEX-101 (3.09 ± 1.14 ng/mL) than control individuals (1.9 ± 0.67 ng/mL), according to the data (p< 0.001). In addition, male infertility exhibited statistically significant higher levels of SPTRXR3 (6.22 ± 1.7 pg/mL) than with healthy individuals (2.84 ± 0.6 pg/mL) (p<0.001). Conclusions: Confirming their importance as markers in male infertility, the measurement of TEX-101 and SPTRX3 concentrations validates their significance
Keywords:TEX-101, SPTRX3, infertility.