Shaymaa Malik Yasir 1, Hanaa Mumtaz Hussein 2, Dalal Abdel-Hussein Kadhim AL–Essawi 3
1Biology Department-College of Education for pure sciences- Kerbala University- Kerbala -Iraq
2Biology Department- Education for Girls Faculty- Kufa University- Iraq
3Biology Department- Education for Girls Faculty- Kufa University- Iraq
ABSTRACT
Study was conducted to determine the role of spasming drug in certain weight and histological parameters of the livers I the embryos and pregnant rats on the 19th day of gestation. The study was carried out in the Education Faculty of Girls at Kufa University during the period of time from January 1, 2022 to June 15, 2022. After obtaining an adequate number of pregnant rats, some were given a dose of a physiological solution, this group represented the control (G1). At the same time, the other animal group of pregnant female rats were given in spasming drug at the dose of (0.48 mg/kg / b.w.) (G2), the pregnant rats in the control group had age (12) weeks and weight (233) grammes, and the pregnant animals in the spasming group had age (11) weeks and weight (229) grammes. Results of the study recorded a significant decrease (P 0.05) in the liver weights of each pregnant animals and embryos in the rat groups treated with the spasming drug during the 19th day of gestation. This was compared with the pregnant rat and embryo liver weights in the regulated groups during gestation for 19th day. Additionally, the results demonstrated that treating pregnant animals with spasming drugs till the 19th day of gestation stimulated various abnormal effects. The conclusion of this study: The treatment of pregnant rats with spasming drugs reduced the weights of their livers. It caused various histopathological changes in the structure of the livers of the embryos and pregnant rats during gestation of the 19th day. Histopathological changes in the structure of the livers of the embryos and pregnant rats during the 19th day of gestation.
Keywords:Spasmine, Weights, Livers, Embryo, Pregnant, Rats, Rattus.