REVIEW
Year : 2006  |  Volume : 5  |  Issue : 1  |  Page : 20

Does architectural lighting contribute to breast cancer?


Lighting Research Center, Rensselaer Polytechnic Institute, 21 Union Street Troy, NY 12180, USA

Correspondence Address:
Mark S Rea
Lighting Research Center, Rensselaer Polytechnic Institute, 21 Union Street Troy, NY 12180
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.1186/1477-3163-5-20

Objectives: There is a growing interest in the role that light plays on nocturnal melatonin production and, perhaps thereby, the incidence of breast cancer in modern societies. The direct causal relationships in this logical chain have not, however, been fully established and the weakest link is an inability to quantitatively specify architectural lighting as a stimulus for the circadian system. The purpose of the present paper is to draw attention to this weakness. Data Sources and Extraction: We reviewed the literature on the relationship between melatonin, light at night, and cancer risk in humans and tumor growth in animals. More specifically, we focused on the impact of light on nocturnal melatonin suppression in humans and on the applicability of these data to women in real-life situations. Photometric measurement data from the lighted environment of women at work and at home is also reported. Data Synthesis: The literature review and measurement data demonstrate that more quantitative knowledge is needed about circadian light exposures actually experienced by women and girls in modern societies. Conclusion: Without such quantitative knowledge, limited insights can be gained about the causal relationship between melatonin and the etiology of breast cancer from epidemiological studies and from parametric studies using animal models.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed10493    
    Printed491    
    Emailed1    
    PDF Downloaded1240    
    Comments [Add]    
    Cited by others 22    

Recommend this journal